Development of directly compressible metformin hydrochloride by the spray-drying technique
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منابع مشابه
Development of directly compressible metformin hydrochloride by the spray-drying technique.
Metformin hydrochloride exhibits poor compressibility during compaction, often resulting in weak and unacceptable tablets with a high tendency to cap. The purpose of this study was to develop directly compressible metformin hydrochloride by the spray-drying technique in the presence of polymer. Metformin hydrochloride was dissolved in solutions containing a polymer, namely polyvinylpyrrolidone ...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2010
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-010-0016-9